Epitalon

Epitalon (also spelled Epithalon) is a synthetic tetrapeptide derived from the pineal gland protein epithalamin. It is one of the most researched peptide bioregulators and the one most associated with longevity science, primarily through decades of Russian research led by the St. Petersburg Institute of Bioregulation and Gerontology. How it works: Epitalon is thought to stimulate telomerase - the enzyme that maintains the protective caps at the ends of chromosomes (telomeres). Telomere shortening is linked to cellular aging. Epitalon may also normalize circadian rhythm and melatonin production, acting through the pineal gland's natural timing function. Both of these mechanisms connect it to the biology of aging. Who tends to use it: People with strong longevity goals use it most, and it also carries a secondary rating for sleep. It is frequently included in broader longevity stacks alongside Thymalin and Pinealon, and it can be paired with MOTS-c as well. It is run once or twice per year as a course, rather than continuously. How it is taken: Epitalon is given by subcutaneous (SC) injection. The general dose range is 5-10 mg per injection. Dosing is daily during a course, in the evening, and courses run 10-20 days. The typical rhythm is 1-2 courses per year. Timing in the evening is consistent with its pineal and circadian connections. What to expect: Most published data comes from Russian studies. The evidence is classified as emerging. Effects are systemic and biological rather than immediately felt - the potential benefits relate to long-term cellular maintenance rather than acute change. Safety: The primary note is that most data comes from Russian research. There are no excludeIf flags and no significant adverse effects are reported in the existing literature. Your licensed provider in the PepDepo network will set your course schedule and confirm the dose at consult.