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Nootropic / anxiolytic

Selank

Calm focus without sedation, the anti-anxiety partner to Semax.

Emerging evidence

Overview

Selank is a synthetic analog of tuftsin, a natural immune-active tetrapeptide. Like Semax, it was developed in Russia, where it has been approved as a prescription medication. In the US it is a research compound. How it works: Selank balances GABA and serotonin activity in the brain. The practical effect is a reduction in anxiety and stress without sedation - you stay alert and sharp while the background noise of worry quiets down. Who tends to use it: People whose main goal is mood and stress resilience, particularly those who find that anxiety is their biggest barrier to clear thinking. Selank also carries a secondary rating for cognition, so it is often paired with Semax when someone wants both calm and focus. How it is taken: Selank is administered intranasally. The general range is 300-900 mcg, dosed once or twice daily. Unlike Semax, timing is flexible - it can be used at any time of day because it does not have the stimulating quality that makes late dosing an issue. Cycles run 2-4 weeks with a break afterward. What to expect: The primary experience is reduced anxiety with preserved mental clarity. It is explicitly non-sedating, which sets it apart from most anxiolytic medications. Safety: Selank is well tolerated. There are no excludeIf flags in the record - no contraindications for pregnancy or cancer history are listed for this peptide. That said, as a research compound in the US, a clinical consult is always appropriate before starting. Your licensed provider in the PepDepo network will determine the right dose and timing at consult based on your full health profile.

At a glance

Route
Intranasal
Dose
300-900 mcg
Frequency
1-2x daily
Timing
Any time
Cycle
2-4 weeks on, break

Combining

Stacks well with: Semax

Safety

Well tolerated; non-sedating.

Regulatory: Approved in Russia; research compound in the US.

Questions

How is Selank taken?⌄

Intranasally - drops applied inside the nostrils. The general range is 300-900 mcg per dose, given once or twice daily.

Will it make me drowsy?⌄

No. The record specifically notes it is non-sedating. It reduces anxiety while keeping you alert, which is what distinguishes it from sedative anxiolytics.

Can I take it at any time of day?⌄

Yes. Unlike Semax, Selank does not have a stimulating quality, so timing is flexible. You can use it morning, afternoon, or evening.

What goals is Selank primarily used for?⌄

Mood and stress resilience is its primary rating. Cognition is a strong secondary. It is not listed for physical goals like recovery or fat loss.

Are there any contraindications?⌄

The record lists no excludeIf flags - no current contraindications for pregnancy or cancer history. It is described as well tolerated. Your clinician will review your full history at consult.

Does it stack well with other peptides?⌄

Selank and Semax are the natural pairing - Semax for focus and mental drive, Selank for calm. Many people use them together during the same cycle.

How long is a typical cycle?⌄

2-4 weeks on, then a break. Cycling is standard practice with this class of peptide.

Related protocols

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Exact dosing is set with a licensed provider in the PepDepo network. This page is education, not a prescription.

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Education only, not medical advice. Peptides discussed are for informational purposes and many are not FDA-approved. Eligibility, prescribing, compounding, and dispensing are handled by appropriately licensed entities. Exact protocols and dosing are set with a licensed provider in the PepDepo network at consult. Content is pending clinical review.